| Dataset | RNR_GSEA_DESEQ2_PVAL |
| Phenotype | NoPhenotypeAvailable |
| Upregulated in class | na_neg |
| GeneSet | V$CREB_02 |
| Enrichment Score (ES) | -0.12056445 |
| Normalized Enrichment Score (NES) | -2.2852774 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.026513942 |
| FWER p-Value | 0.203 |

| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | PCSK2 | 225 | 0.990 | -0.0082 | No | ||
| 2 | CHGB | 322 | 0.983 | -0.0093 | No | ||
| 3 | NAPA | 395 | 0.978 | -0.0092 | No | ||
| 4 | NKX6-1 | 462 | 0.974 | -0.0087 | No | ||
| 5 | SEC24D | 478 | 0.973 | -0.0055 | No | ||
| 6 | POLDIP3 | 488 | 0.972 | -0.0019 | No | ||
| 7 | XPNPEP1 | 507 | 0.972 | 0.0012 | No | ||
| 8 | MRRF | 610 | 0.966 | -0.0003 | No | ||
| 9 | WNT10A | 675 | 0.963 | 0.0003 | No | ||
| 10 | UBE2D3 | 785 | 0.958 | -0.0016 | No | ||
| 11 | HDAC6 | 851 | 0.954 | -0.0010 | No | ||
| 12 | XPNPEP3 | 1049 | 0.945 | -0.0077 | No | ||
| 13 | C11orf87 | 1072 | 0.943 | -0.0048 | No | ||
| 14 | NR4A2 | 1293 | 0.930 | -0.0127 | No | ||
| 15 | CNTROB | 1380 | 0.926 | -0.0133 | No | ||
| 16 | VPS37A | 1556 | 0.917 | -0.0188 | No | ||
| 17 | CORO6 | 1629 | 0.913 | -0.0186 | No | ||
| 18 | TMEM86A | 1725 | 0.908 | -0.0197 | No | ||
| 19 | IL1RAPL1 | 2610 | 0.861 | -0.0637 | No | ||
| 20 | SREBF2 | 2676 | 0.858 | -0.0632 | No | ||
| 21 | IFT20 | 2705 | 0.856 | -0.0607 | No | ||
| 22 | KLHL12 | 2735 | 0.854 | -0.0582 | No | ||
| 23 | ARMCX1 | 2950 | 0.842 | -0.0658 | No | ||
| 24 | QRICH1 | 3105 | 0.833 | -0.0701 | No | ||
| 25 | NOL10 | 3221 | 0.825 | -0.0723 | No | ||
| 26 | LYPD3 | 3231 | 0.825 | -0.0687 | No | ||
| 27 | GLYR1 | 3396 | 0.817 | -0.0735 | No | ||
| 28 | GRM3 | 3421 | 0.816 | -0.0708 | No | ||
| 29 | WBP5 | 3583 | 0.808 | -0.0755 | No | ||
| 30 | ANAPC2 | 3638 | 0.804 | -0.0744 | No | ||
| 31 | LAYN | 3689 | 0.801 | -0.0730 | No | ||
| 32 | RNF44 | 3746 | 0.798 | -0.0720 | No | ||
| 33 | RCE1 | 3838 | 0.793 | -0.0729 | No | ||
| 34 | SDHB | 3846 | 0.793 | -0.0692 | No | ||
| 35 | GEM | 3868 | 0.791 | -0.0663 | No | ||
| 36 | ATG5 | 3902 | 0.790 | -0.0640 | No | ||
| 37 | DUSP1 | 3953 | 0.787 | -0.0626 | No | ||
| 38 | SMARCD1 | 3975 | 0.786 | -0.0597 | No | ||
| 39 | DDX51 | 4085 | 0.780 | -0.0616 | No | ||
| 40 | JUND | 4090 | 0.779 | -0.0577 | No | ||
| 41 | SLC20A2 | 4167 | 0.775 | -0.0578 | No | ||
| 42 | PPP2R2A | 4208 | 0.773 | -0.0559 | No | ||
| 43 | SNAPC5 | 4426 | 0.761 | -0.0637 | No | ||
| 44 | LMBRD1 | 4497 | 0.758 | -0.0634 | No | ||
| 45 | ZFYVE27 | 4516 | 0.757 | -0.0603 | No | ||
| 46 | SAMD12 | 4661 | 0.748 | -0.0641 | No | ||
| 47 | ZNF593 | 4768 | 0.743 | -0.0658 | No | ||
| 48 | SLC35E1 | 4838 | 0.739 | -0.0655 | No | ||
| 49 | HMGB1 | 4994 | 0.729 | -0.0698 | No | ||
| 50 | PRKCH | 5035 | 0.726 | -0.0679 | No | ||
| 51 | PTPN23 | 5112 | 0.722 | -0.0680 | No | ||
| 52 | RUNDC3A | 5134 | 0.720 | -0.0651 | No | ||
| 53 | GNL1 | 5138 | 0.720 | -0.0612 | No | ||
| 54 | ERF | 5280 | 0.712 | -0.0648 | No | ||
| 55 | ST13 | 5298 | 0.710 | -0.0617 | No | ||
| 56 | SMS | 5409 | 0.706 | -0.0636 | No | ||
| 57 | PPP1R15A | 5525 | 0.699 | -0.0658 | No | ||
| 58 | NEUROD6 | 5574 | 0.697 | -0.0643 | No | ||
| 59 | CALM2 | 5650 | 0.693 | -0.0643 | No | ||
| 60 | PELP1 | 5743 | 0.689 | -0.0653 | No | ||
| 61 | HNRNPAB | 5973 | 0.677 | -0.0737 | No | ||
| 62 | CRH | 6150 | 0.667 | -0.0792 | No | ||
| 63 | TMEM39A | 6193 | 0.665 | -0.0774 | No | ||
| 64 | YWHAZ | 6436 | 0.652 | -0.0865 | No | ||
| 65 | PNMA6A | 6554 | 0.646 | -0.0888 | No | ||
| 66 | MESDC1 | 6560 | 0.645 | -0.0850 | No | ||
| 67 | PAK1 | 6592 | 0.643 | -0.0826 | No | ||
| 68 | ARTN | 6795 | 0.631 | -0.0895 | No | ||
| 69 | FAM174A | 6985 | 0.622 | -0.0957 | No | ||
| 70 | BRE | 7116 | 0.614 | -0.0987 | No | ||
| 71 | TP53INP2 | 7224 | 0.608 | -0.1005 | No | ||
| 72 | SSTR3 | 7243 | 0.607 | -0.0974 | No | ||
| 73 | PAK3 | 7254 | 0.607 | -0.0939 | No | ||
| 74 | DDX28 | 7299 | 0.605 | -0.0922 | No | ||
| 75 | PHF15 | 7388 | 0.600 | -0.0929 | No | ||
| 76 | AKIRIN1 | 7392 | 0.600 | -0.0890 | No | ||
| 77 | POLB | 7468 | 0.596 | -0.0891 | No | ||
| 78 | EVX1 | 7528 | 0.593 | -0.0882 | No | ||
| 79 | LGR5 | 7566 | 0.592 | -0.0862 | No | ||
| 80 | PITX2 | 7596 | 0.590 | -0.0837 | No | ||
| 81 | DCTN1 | 7712 | 0.583 | -0.0859 | No | ||
| 82 | TPT1 | 7850 | 0.576 | -0.0892 | No | ||
| 83 | RBKS | 7868 | 0.575 | -0.0861 | No | ||
| 84 | TNFAIP1 | 8007 | 0.567 | -0.0895 | No | ||
| 85 | OSBP | 8041 | 0.566 | -0.0873 | No | ||
| 86 | RNF166 | 8184 | 0.558 | -0.0909 | No | ||
| 87 | IRF2BPL | 8340 | 0.549 | -0.0953 | No | ||
| 88 | UMPS | 8366 | 0.548 | -0.0926 | No | ||
| 89 | RNMTL1 | 8404 | 0.546 | -0.0905 | No | ||
| 90 | PHF8 | 8513 | 0.539 | -0.0923 | No | ||
| 91 | C12orf66 | 8742 | 0.526 | -0.1007 | No | ||
| 92 | ARMCX6 | 8778 | 0.524 | -0.0985 | No | ||
| 93 | SHANK2 | 8828 | 0.522 | -0.0971 | No | ||
| 94 | ASPHD1 | 8870 | 0.519 | -0.0953 | No | ||
| 95 | EIF5A | 8949 | 0.514 | -0.0955 | No | ||
| 96 | ADAP1 | 9104 | 0.505 | -0.0998 | No | ||
| 97 | NINJ1 | 9191 | 0.501 | -0.1004 | No | ||
| 98 | SLC30A5 | 9271 | 0.497 | -0.1006 | No | ||
| 99 | YTHDC2 | 9364 | 0.492 | -0.1016 | No | ||
| 100 | CNOT7 | 9440 | 0.488 | -0.1016 | No | ||
| 101 | AGPAT1 | 9588 | 0.480 | -0.1055 | No | ||
| 102 | PPM1A | 9670 | 0.476 | -0.1058 | No | ||
| 103 | MED27 | 9672 | 0.475 | -0.1018 | No | ||
| 104 | GLI1 | 9732 | 0.472 | -0.1010 | No | ||
| 105 | ERC1 | 9783 | 0.469 | -0.0996 | No | ||
| 106 | PAFAH1B1 | 9935 | 0.459 | -0.1038 | No | ||
| 107 | FOXD3 | 9975 | 0.457 | -0.1018 | No | ||
| 108 | C4orf21 | 10126 | 0.449 | -0.1059 | No | ||
| 109 | SNAP25 | 10221 | 0.443 | -0.1070 | No | ||
| 110 | C9orf3 | 10305 | 0.438 | -0.1074 | No | ||
| 111 | MDN1 | 10345 | 0.437 | -0.1055 | No | ||
| 112 | HHIP | 10353 | 0.437 | -0.1018 | No | ||
| 113 | PDLIM3 | 10405 | 0.433 | -0.1005 | No | ||
| 114 | KDELR1 | 10463 | 0.430 | -0.0995 | No | ||
| 115 | TRAPPC1 | 10523 | 0.427 | -0.0987 | No | ||
| 116 | NUP98 | 10663 | 0.420 | -0.1022 | No | ||
| 117 | NOL4 | 10775 | 0.414 | -0.1042 | No | ||
| 118 | VAMP2 | 10818 | 0.411 | -0.1024 | No | ||
| 119 | KDELR3 | 10887 | 0.408 | -0.1020 | No | ||
| 120 | THADA | 10931 | 0.406 | -0.1003 | No | ||
| 121 | RNF40 | 10978 | 0.404 | -0.0987 | No | ||
| 122 | SNRPG | 11193 | 0.391 | -0.1063 | No | ||
| 123 | ZC3H18 | 11265 | 0.387 | -0.1061 | No | ||
| 124 | PRR3 | 11320 | 0.384 | -0.1050 | No | ||
| 125 | DAD1 | 11343 | 0.383 | -0.1021 | No | ||
| 126 | PLK4 | 11509 | 0.374 | -0.1070 | No | ||
| 127 | SCAMP5 | 11612 | 0.368 | -0.1085 | No | ||
| 128 | LHX5 | 11639 | 0.367 | -0.1058 | No | ||
| 129 | PRICKLE2 | 11669 | 0.365 | -0.1033 | No | ||
| 130 | FBXL19 | 11812 | 0.355 | -0.1070 | No | ||
| 131 | MAP1LC3A | 12024 | 0.343 | -0.1144 | No | ||
| 132 | C5orf15 | 12053 | 0.342 | -0.1119 | No | ||
| 133 | PHF20L1 | 12080 | 0.340 | -0.1092 | No | ||
| 134 | SGIP1 | 12157 | 0.335 | -0.1093 | No | ||
| 135 | THOC1 | 12194 | 0.333 | -0.1072 | No | ||
| 136 | ABHD16A | 12207 | 0.333 | -0.1038 | No | ||
| 137 | RPS29 | 12288 | 0.328 | -0.1041 | No | ||
| 138 | TIPRL | 12491 | 0.316 | -0.1110 | No | ||
| 139 | BIN3 | 12501 | 0.315 | -0.1074 | No | ||
| 140 | GTF2H1 | 12595 | 0.310 | -0.1084 | No | ||
| 141 | CLDN7 | 12598 | 0.310 | -0.1044 | No | ||
| 142 | RNF5 | 12726 | 0.302 | -0.1073 | No | ||
| 143 | VPS37B | 12737 | 0.301 | -0.1038 | No | ||
| 144 | GSC | 12804 | 0.297 | -0.1033 | No | ||
| 145 | FAM65A | 12872 | 0.294 | -0.1029 | No | ||
| 146 | DENND5A | 13005 | 0.286 | -0.1060 | No | ||
| 147 | RBM18 | 13274 | 0.272 | -0.1165 | Yes | ||
| 148 | KDELR2 | 13278 | 0.271 | -0.1126 | Yes | ||
| 149 | RBBP8 | 13297 | 0.270 | -0.1095 | Yes | ||
| 150 | IRX4 | 13413 | 0.264 | -0.1117 | Yes | ||
| 151 | CBLL1 | 13471 | 0.262 | -0.1107 | Yes | ||
| 152 | C1orf27 | 13482 | 0.261 | -0.1072 | Yes | ||
| 153 | C6orf106 | 13546 | 0.258 | -0.1066 | Yes | ||
| 154 | UBE2H | 13621 | 0.252 | -0.1065 | Yes | ||
| 155 | MAFF | 13633 | 0.252 | -0.1031 | Yes | ||
| 156 | ZFY | 13641 | 0.251 | -0.0994 | Yes | ||
| 157 | SEZ6L2 | 13708 | 0.248 | -0.0989 | Yes | ||
| 158 | USP36 | 13739 | 0.246 | -0.0965 | Yes | ||
| 159 | SCFD2 | 13800 | 0.242 | -0.0957 | Yes | ||
| 160 | USP48 | 13828 | 0.240 | -0.0931 | Yes | ||
| 161 | FLT1 | 13837 | 0.240 | -0.0895 | Yes | ||
| 162 | ZFAND2B | 13860 | 0.239 | -0.0866 | Yes | ||
| 163 | PDP1 | 13940 | 0.235 | -0.0868 | Yes | ||
| 164 | FOSB | 13958 | 0.234 | -0.0837 | Yes | ||
| 165 | ISCU | 14005 | 0.232 | -0.0821 | Yes | ||
| 166 | MBNL2 | 14318 | 0.214 | -0.0950 | Yes | ||
| 167 | CDC42 | 14330 | 0.214 | -0.0915 | Yes | ||
| 168 | MMGT1 | 14367 | 0.212 | -0.0894 | Yes | ||
| 169 | GTPBP10 | 14377 | 0.211 | -0.0859 | Yes | ||
| 170 | SRP54 | 14403 | 0.209 | -0.0832 | Yes | ||
| 171 | EEF2 | 14437 | 0.207 | -0.0809 | Yes | ||
| 172 | CENPE | 14560 | 0.201 | -0.0835 | Yes | ||
| 173 | DLST | 14674 | 0.195 | -0.0855 | Yes | ||
| 174 | CHD2 | 14728 | 0.192 | -0.0844 | Yes | ||
| 175 | SHKBP1 | 14812 | 0.188 | -0.0848 | Yes | ||
| 176 | CCDC41 | 14943 | 0.181 | -0.0878 | Yes | ||
| 177 | ARIH1 | 14949 | 0.180 | -0.0840 | Yes | ||
| 178 | NF1 | 15031 | 0.176 | -0.0844 | Yes | ||
| 179 | EPHA2 | 15061 | 0.174 | -0.0819 | Yes | ||
| 180 | RING1 | 15135 | 0.169 | -0.0818 | Yes | ||
| 181 | AHR | 15168 | 0.168 | -0.0795 | Yes | ||
| 182 | CAMK2D | 15211 | 0.166 | -0.0777 | Yes | ||
| 183 | RAB25 | 15431 | 0.155 | -0.0855 | Yes | ||
| 184 | BRMS1 | 15670 | 0.143 | -0.0944 | Yes | ||
| 185 | CDC14B | 15673 | 0.143 | -0.0904 | Yes | ||
| 186 | TSC22D2 | 15675 | 0.143 | -0.0864 | Yes | ||
| 187 | SPAG9 | 15734 | 0.140 | -0.0855 | Yes | ||
| 188 | SSBP3 | 15827 | 0.135 | -0.0865 | Yes | ||
| 189 | MAP3K13 | 15840 | 0.134 | -0.0831 | Yes | ||
| 190 | DHX36 | 15928 | 0.128 | -0.0837 | Yes | ||
| 191 | SMARCAD1 | 16076 | 0.120 | -0.0877 | Yes | ||
| 192 | PHACTR3 | 16121 | 0.117 | -0.0860 | Yes | ||
| 193 | DHX40 | 16160 | 0.116 | -0.0840 | Yes | ||
| 194 | HIST1H4E | 16182 | 0.115 | -0.0811 | Yes | ||
| 195 | ID1 | 16214 | 0.113 | -0.0787 | Yes | ||
| 196 | RFC1 | 16217 | 0.113 | -0.0747 | Yes | ||
| 197 | CYLD | 16319 | 0.107 | -0.0762 | Yes | ||
| 198 | CCNI | 16617 | 0.092 | -0.0882 | Yes | ||
| 199 | C7orf55 | 16620 | 0.092 | -0.0843 | Yes | ||
| 200 | MRGPRF | 16664 | 0.089 | -0.0826 | Yes | ||
| 201 | PNMA3 | 16682 | 0.088 | -0.0794 | Yes | ||
| 202 | NOC4L | 16695 | 0.087 | -0.0760 | Yes | ||
| 203 | RAB2A | 16737 | 0.085 | -0.0742 | Yes | ||
| 204 | NR4A3 | 16749 | 0.084 | -0.0707 | Yes | ||
| 205 | GPR3 | 16762 | 0.084 | -0.0673 | Yes | ||
| 206 | SIK1 | 16790 | 0.082 | -0.0647 | Yes | ||
| 207 | PHF17 | 16834 | 0.080 | -0.0630 | Yes | ||
| 208 | BRAF | 16883 | 0.077 | -0.0615 | Yes | ||
| 209 | SULT4A1 | 16897 | 0.077 | -0.0582 | Yes | ||
| 210 | FBXL2 | 16980 | 0.072 | -0.0586 | Yes | ||
| 211 | CLDN6 | 17041 | 0.069 | -0.0578 | Yes | ||
| 212 | HPS5 | 17095 | 0.067 | -0.0566 | Yes | ||
| 213 | NR2E1 | 17103 | 0.066 | -0.0529 | Yes | ||
| 214 | KPTN | 17145 | 0.064 | -0.0510 | Yes | ||
| 215 | CD2AP | 17215 | 0.061 | -0.0507 | Yes | ||
| 216 | PCIF1 | 17392 | 0.052 | -0.0562 | Yes | ||
| 217 | SSNA1 | 17457 | 0.049 | -0.0557 | Yes | ||
| 218 | RBP5 | 17475 | 0.048 | -0.0525 | Yes | ||
| 219 | YTHDF3 | 17499 | 0.047 | -0.0497 | Yes | ||
| 220 | GTF2A1 | 17503 | 0.046 | -0.0458 | Yes | ||
| 221 | ELL2 | 17552 | 0.044 | -0.0444 | Yes | ||
| 222 | SCG2 | 17609 | 0.041 | -0.0433 | Yes | ||
| 223 | ZFAND5 | 17687 | 0.037 | -0.0435 | Yes | ||
| 224 | TSPAN7 | 17695 | 0.037 | -0.0398 | Yes | ||
| 225 | NARG2 | 17698 | 0.037 | -0.0358 | Yes | ||
| 226 | UBA6 | 17774 | 0.034 | -0.0358 | Yes | ||
| 227 | MUT | 17775 | 0.034 | -0.0318 | Yes | ||
| 228 | CTNND2 | 17793 | 0.033 | -0.0286 | Yes | ||
| 229 | ALS2 | 17816 | 0.032 | -0.0258 | Yes | ||
| 230 | MAGI1 | 17937 | 0.027 | -0.0282 | Yes | ||
| 231 | ZNF23 | 17976 | 0.025 | -0.0262 | Yes | ||
| 232 | C12orf5 | 17988 | 0.024 | -0.0228 | Yes | ||
| 233 | CLSTN3 | 18036 | 0.022 | -0.0212 | Yes | ||
| 234 | PPARGC1A | 18057 | 0.021 | -0.0183 | Yes | ||
| 235 | SRSF1 | 18108 | 0.018 | -0.0169 | Yes | ||
| 236 | SMARCA5 | 18120 | 0.017 | -0.0135 | Yes | ||
| 237 | TAGLN2 | 18132 | 0.017 | -0.0100 | Yes | ||
| 238 | HS3ST3A1 | 18155 | 0.016 | -0.0071 | Yes | ||
| 239 | SOX12 | 18223 | 0.013 | -0.0067 | Yes | ||
| 240 | SART3 | 18289 | 0.010 | -0.0062 | Yes | ||
| 241 | XPR1 | 18305 | 0.010 | -0.0029 | Yes | ||
| 242 | TPR | 18364 | 0.008 | -0.0020 | Yes | ||
| 243 | SPRED2 | 18404 | 0.006 | -0.0001 | Yes | ||
| 244 | IVNS1ABP | 18426 | 0.005 | 0.0029 | Yes | ||
| 245 | RCAN1 | 18438 | 0.005 | 0.0063 | Yes | ||
| 246 | FDXR | 18514 | 0.002 | 0.0063 | Yes |
